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本文对未经补碘防治的IDD病区7~14岁儿童用碘油丸三种剂量分两次投药方法,以尿碘(UI)、FT3、FT4、TSH及甲状腺肿大率、患病率、发病率、有效率、治愈率为指标,经给药后半年、1年、2年、3年随访对比研究,发现各组有效期均能维持3年。但达标控制有效期大、中、小剂量组分别为3年、2年、1年。此应视为各组的防治周期。剂量和周期的选择认为边远防治条件差的重病区宜大剂量2~3年为周期;一般地区可选中剂量2年为周期;而轻病区,条件好的病区可选小剂量1年为周期的方法应属可取。大剂量者第2次投药时间取1年,可避免高碘损伤之顾虑和碘的排出过多过快之浪费。且可望维持效果更长的时间。
In this paper, IDD wards without iodine control in children aged 7 to 14 years old with iodized oil pills three doses in two doses, urine iodine (UI), FT3, FT4, TSH and goiter rate, prevalence, Incidence rate, effective rate and cure rate were taken as indexes. After 6 months, 1 year, 2 years and 3 years follow-up after administration, it was found that the effective period of each group could be maintained for 3 years. However, the effective control of large, medium and small dose groups were 3 years, 2 years, 1 year. This should be considered as the control cycle of each group. Dose and cycle options that the remote control of poor conditions should be high-dose of heavy dose of 2 to 3 years for the cycle; the general area of choice for two-year dose of the cycle; and light area, well-ward optional small dose of 1 year The method of the cycle should be desirable. Large doses of the second dosing time taken 1 year, to avoid the concerns of high iodine damage and excessive discharge of iodine waste. And is expected to maintain longer effect.