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抗真菌剂包括化学合成制剂和抗菌素两大类。真菌感染的化学疗法始于用灰黄霉素治疗絮状表皮癣菌和用两性霉素B治疗深部真菌病,以后研制成的抗真菌药物尚有克霉唑和5-氟胞嘧啶等。一、化学合成制剂1.碘制剂:碘制剂是治疗真菌病的最古老药物,它对孢子丝虫病有效(仅对淋巴管炎型有效,对肺炎型则无效)。复方碘溶液(1克/毫升)稀释后口服,每日2～4毫升,从小剂量开始逐渐加量,持续3～4周。多量服用时,可因胃肠功能障碍、发热等而不能耐受。其他副作用尚有皮疹、血
Antifungal agents include chemical synthesis and antibiotics two broad categories. Fungal infection of chemotherapy began with griseofulvin treatment of Epidermophyton floccosum and amphotericin B treatment of deep fungal disease, later developed anti-fungal drugs are clotrimazole and 5-fluorocytosine and so on. First, the chemical synthesis of agents 1. Iodine agents: iodine agent is the oldest drug treatment of fungal diseases, it is effective against sporo-filariasis (lymphatic tube type effective only, is invalid for pneumonia type). Compound iodine solution (1 g / ml) diluted oral, 2 to 4 ml daily, starting from the small dose gradually increase for 3 to 4 weeks. When taken in large quantities, due to gastrointestinal dysfunction, fever and can not tolerate. Other side effects still rash, blood