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目的:观察降钙素原(PCT)在新生儿细菌感染性疾病早期诊断中的意义。方法:选取黔南州人民医院2014年10月至2015年10月收治的50例新生儿,在征得患儿知情同意下随机分为对照组及观察组各25例,对照组为正常新生儿,观察组为患有细菌感染性疾病的新生儿,检查两组患儿的PCT以及超敏C-反应蛋白(hs-CRR),比较两组患儿的临床疗效。结果:观察组患儿的降钙素原以及hs-CRR的检测结果均高于对照组,两组差异具有统计学意义(P<0.05);观察组中PCT以及hs-CRR呈现阳性的人数中,PCT呈现阳性的人数远超于hs-CRR呈现阳性的人数,差异具有统计学意义(P<0.05)。结论:使用PCT进行细菌感染性疾病的早期判定效果优于使用hs-CRR对新生儿患有细菌感染性疾病的早期判定。
Objective: To investigate the significance of procalcitonin (PCT) in the early diagnosis of neonatal bacterial infectious diseases. Methods: Fifty newborns admitted to Qiannan People’s Hospital from October 2014 to October 2015 were selected and randomly divided into control group and observation group (n = 25). The control group was normal newborn , The observation group was a newborn with bacterial infection, the PCT and hs-CRR in both groups were examined, and the clinical efficacy was compared between the two groups. Results: The detection of procalcitonin and hs-CRR in the observation group were higher than those in the control group, the difference was statistically significant (P <0.05); in the observation group, the number of PCT and hs-CRR positive , The number of patients with positive PCT was far more than the number of patients with positive hs-CRR, the difference was statistically significant (P <0.05). CONCLUSIONS: The use of PCT for early detection of bacterial infectious diseases is superior to the early determination of neonatal bacterial infections due to the use of hs-CRR.