本文报告１例在华法林(Ｗａｌｆａｒｉｎ)疗法中出现皮肤坏死和阴茎勃起的病人。病例 男,１６岁,体重６０ｋｇ,突发左下肢小腿肿胀和疼痛,超声波检查发现腘静脉至浅股静脉血栓形成,持续静脉滴注肝素治疗,并于第５天开始给予华法林１０ｍｇ/ｄ,然而第６天部分凝血活酶时间是正常２．３倍,腿痛加重,腿、脚 This article reports 1 patient who developed skin necrosis and penile erection in Walfarin therapy. A 16-year-old male with a body weight of 60 kg developed swollen and painful leg in the left lower extremity. Sonography was performed to detect thrombosis of the popliteal vein to the superficial femoral vein by continuous intravenous infusion of heparin. On day 5, warfarin 10 mg / d , But the sixth day partial thromboplastin time is 2.3 times normal, leg pain increased, legs and feet