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目的：用超声造影剂利声显增强显像， 观察原发性肝癌逆行肝动脉插管栓塞化疗（ＴＡＥ）前后肿瘤图像的彩色多普勒信号变化。方法： 使用ＨＰＳｏｎｏｓ ２５００型彩超仪， 探头频率２．５ＭＨｚ， 仪器检查条件一致， 对２０例原发性肝癌患者于ＴＡＥ治疗前和治疗后５～７日内各检查１次， 每次检查使用１支利声显， 增强结果用两种方法评价。结果： ＴＡＥ治疗前， 肿瘤血供丰富， 利声显增强效果明显； ＴＡＥ治疗后， 肿瘤血供减少， 尽管利声显增强效果确实，彩色信号仍明显减弱。计算机数字化显示ＴＡＥ治疗前利声显增强前后肿瘤内彩色点的百分比值为５．１９±４．８５Ｖｓ ２６．５２±１５．８３， ＴＡＥ治疗后利声显增强前后肿瘤内彩色点的百分比值为１．４２±１．１１ Ｖｓ１０．２７±７．３８。结论： 利声显对肝癌肿瘤的彩色多普勒信号具有确实的增强效果； ＴＡＥ治疗后， 肝癌肿瘤彩色多普勒信号明显减少； 用计算机分析利声显的增强效果， 结果更加直观、可靠， 对判断ＴＡＥ疗效具有实际的临床价值和意义。
OBJECTIVE: To evaluate the color Doppler signal of tumor images before and after retrograde hepatic artery embolization chemotherapy (TAE) in primary hepatocellular carcinoma with enhanced ultrasound contrast-enhanced ultrasound imaging. Methods: Using the HP Sonos 2500 Color Doppler Ultrasound System, the probe frequency was 2.5 MHz. The instrument examination conditions were consistent. 20 patients with primary liver cancer were examined before and 5 to 7 days after TAE treatment. Each examination used 1 The sound is pronounced and the enhancement results are evaluated in two ways. Results: Before TAE treatment, the tumor blood supply was abundant, and the sound enhancement effect was obvious. After TAE treatment, the blood supply of the tumor was reduced. Despite the fact that the sound enhancement effect was positive, the color signal was still significantly reduced. The computer numerical display showed that the percentage of color points in the tumor before and after TAE treatment was significantly improved was 5.19±4.85Vs and 26.52±15.83. The percentage of color points in the tumor before and after TAE treatment was significantly enhanced. 1.42±1.11 Vs10.27±7.38. Conclusions: Lishengxian has a definite enhancement effect on the color Doppler signals of liver cancer tumors; after TAE treatment, the color Doppler signal of liver cancer tumors is significantly reduced; the enhancement effect of the cortical acoustic imaging is analyzed by computer, and the result is more intuitive and reliable. It is of practical clinical value and significance to determine the efficacy of TAE.