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目的探讨饮酒量与男性2型糖尿病患者勃起功能障碍(ED)的相关性。方法对2007年4月至2010年1月在沈阳军区总医院内分泌科住院的400例男性2型糖尿病患者进行问卷调查,采用勃起功能国际指数(IIEF-5)评分问卷对其勃起功能进行评分,按照患者饮酒量进行分组。比较大量饮酒组、适量饮酒组、不饮酒组的基础信息和勃起功能。结果三组糖尿病患者中年龄、空腹血糖、糖化血红蛋白(HbA1c)、胰岛素抵抗指数(HOMA-IR)、体重指数(BMI)、血压、雌激素、睾酮比较差异无统计学意义,三组糖尿病患者糖尿病病程、血管和神经并发症方面比较差异亦无统计学意义。大量饮酒组中ED患病率为83.42%,适量饮酒组中ED患病率为51.11%,不饮酒组中ED患病率为53.70%;大量饮酒组与适量饮酒组比较差异有统计学意义,大量饮酒组与不饮酒组比较差异有统计学意义,而适量饮酒组与不饮酒组比较差异无统计学意义。结论酒精的大量摄入可能是男性2型糖尿病患者ED患病率增加的一个重要因素。
Objective To investigate the correlation between alcohol consumption and erectile dysfunction (ED) in male patients with type 2 diabetes mellitus. Methods A total of 400 male patients with type 2 diabetes mellitus who were hospitalized in Department of Endocrinology, Shenyang Military Region General Hospital from April 2007 to January 2010 were surveyed. The erectile function was scored using the IIEF-5 score questionnaire, According to the patient’s drinking volume grouping. Comparison of a large number of drinking group, moderate drinking group, non-drinking group based information and erectile function. Results There were no significant differences in age, fasting blood glucose, HbA1c, HOMA-IR, BMI, blood pressure, estrogen and testosterone in the three groups of diabetic patients. There was no significant difference between the three groups of patients with diabetes mellitus No significant difference was found in the course of disease, vascular and neurological complications. The prevalence of ED was 83.42% in the drinking group, 51.11% in the moderate drinking group and 53.70% in the non-drinking group. There was significant difference between the heavy drinking group and the moderate drinking group, There was significant difference between a large number of drinking groups and non-drinking groups, but there was no significant difference between moderate drinking groups and non-drinking groups. Conclusions The large intake of alcohol may be an important factor for the increase of ED prevalence in type 2 diabetic men.