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目的：选择高效经济的治疗消化性溃疡的临床新药。方法：对９４ 例消化性溃疡的门诊患者按就诊顺序随机分Ａ、Ｂ 两组，分别以雷尼替丁四联疗法和奥美拉唑四联疗法进行临床治疗，观察两组对象用药后的临床疗效、毒副作用及药物费用。结果：雷尼替丁四联疗法和奥美拉唑四联疗法在临床疗效及毒副作用等方面差异无显著性（ Ｐ＞ ０ ．０５） ，药物费用后者大于前４ 倍。结论：雷尼替丁四联疗法为临床治疗消化性溃疡的首选方案。
Objective: To choose a new and effective clinical drug for the treatment of peptic ulcer. Methods: Ninety-four outpatients with peptic ulcer were randomly divided into groups A and B according to the order of treatment. The patients were treated with ranitidine quadruple therapy and omeprazole quadruple therapy, respectively. After treatment, Clinical efficacy, side effects and drug costs. Results: Ranitidine quadruple therapy and omeprazole quadruple therapy showed no significant difference in clinical efficacy and side effects (P> 0.05), and the cost of drugs was higher than the former four times. Conclusion: Ranitidine quadruple therapy is the first choice for clinical treatment of peptic ulcer.