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采用镀钢镉还原测定沿检测５７倒腹水患者血清和腹水中一氧化氮（ＮＯ）水平，并动态监测其中１９例肝硬化Ｈ发性细菌性腹膜炎（ＳＢＰ）患者治疗前后血和腹水ＮＯ水平及腹水ＮＯ与血ＮＯ比值（ＮＯＡ／ＮＯＢ）变化。结果显示：肝硬化ＳＢＰ漏出性腹水组中，腹水ＮＯ水平和ＮＯＡ／ＮＯＢ值明显高于漏出性腹水组。若以ＮＯＡ／ＮＯＢ≥１．１为阳性判别值，诊断ＳＢＰ的敏感性为８１．５％，特异性为８９．５％。１９例ＳＢＰ患者经抗感染治疗后，腹水ＮＯ水平和ＮＯＡ／ＮＯＢ比值较治疗前明显降低。表明动态监测肝硬化患者腹水与血清ＮＯ水平和二者比值的变化，对肝硬化ＳＢＰ的诊断和预后判断均有一定价值。
The level of nitric oxide (NO) in sera and ascites of 57 ascites patients was detected by plated-cadmium reduction assay. The levels of NO in blood and ascites of 19 patients with cirrhosis and bacterial ascites (SBP) Ascites NO and blood NO ratio (NOA / NOB) changes. The results showed that ascites NO level and NOA / NOB level were significantly higher in ascites group than in ascites group. If the NOA / NOB≥1.1 positive discriminant value, the diagnostic sensitivity of SBP was 81.5%, the specificity was 89.5%. In 19 patients with SBP after anti-infective treatment, the ascites NO level and NOA / NOB ratio was significantly lower than before treatment. It shows that dynamic monitoring of ascites and serum NO levels in patients with cirrhosis and the ratio between the two changes in the diagnosis and prognosis of cirrhotic patients with SBP have some value.