论文部分内容阅读
目的：评价血清Ｃ反应蛋白定量检测对急性心肌梗死（ＡＭＩ）患者预后的判断价值。方法：对９２例ＡＭＩ患者进行血清Ｃ反应蛋白（ＣＲＰ）、肌酸磷酸激酶（ＣＰＫ）及其同功酶（ＣＫ－ＭＢ）测定，并观察Ｃ反应蛋白浓度的高低对ＡＭＩ预后的影响。结果：９２例ＡＭＩ患者中，ＣＲＰ＜２０ｍｇ／Ｌ者４８例，ＣＲＰ＞２０ｍｇ／Ｌ者４４例。两组患者ＣＰＫ、ＣＫ－ＭＢ检测结果，其峰值及变化时程差异无显著性（Ｐ＞０．０５）。９２例ＡＭＩ患者中，ＣＲＰ＞２０ｍｇ／Ｌ组，随访６个月内心脏事件（包括心脏性碎死、阵发性室速、急性左心衰竭、心肌再梗死、顽固性心绞痛等）发生率为８１．８％，ＣＲＰ＜２０ｍｇ／Ｌ组为４１．７％，两组差异有显著性（Ｐ＜０．０１）。结论：ＣＲＰ＞２０ｍｇ／Ｌ对判断ＡＭＩ患者预后有较好的预报价值。
Objective: To evaluate the value of quantitative determination of serum C-reactive protein in the prognosis of patients with acute myocardial infarction (AMI). Methods: Serum C-reactive protein (CRP) and creatine phosphokinase (CK-MB) were measured in 92 AMI patients and the effect of C-reactive protein on the prognosis of AMI was observed. Results: Of the 92 AMI patients, 48 had CRP <20 mg / L and 44 had CRP> 20 mg / L. There was no significant difference between the two groups in CPK and CK-MB test results (P> 0.05). 92 patients with AMI, CRP> 20mg / L group, followed up for 6 months, the incidence of cardiac events (including cardiac crush, paroxysmal ventricular tachycardia, acute left heart failure, myocardial infarction, refractory angina, etc.) 81.8%, CRP <20mg / L group was 41.7%, there was significant difference between the two groups (P <0.01). Conclusion: CRP> 20mg / L has a good predictive value in judging the prognosis of AMI patients.