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[目的]观察天麻素注射液联合长春西汀治疗椎-基底动脉供血不足性眩晕疗效。[方法]使用随机平行对照方法,将110例住院及门诊患者按就诊顺序号抽签方法简单随机分为两组。对照组55例长春西汀,开始20mg+0.5%葡萄糖溶液500m L,1次/d,缓慢静滴,以后根据病情可增至30mg/d。治疗组55例天麻素注射液150mg/次,2次/d,肌注;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、椎动脉血流速度、基底动脉血流速度、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组痊愈22例,显效19例,有效11例,无效3例,总有效率94.55%。对照组痊愈19例,显效17例,有效9例,无效10例,总有效率81.82%。治疗组疗效优于对照组(P<0.05)。椎动脉、基底动脉血流速度两组均有改善(P<0.05,P<0.01),治疗组改善优于对照组(P<0.01)。[结论]天麻素注射液联合长春西汀治疗椎-基底动脉供血不足性眩晕,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of gastrodine injection combined with vinpocetine on vertigo-basilar insufficiency vertigo. [Methods] Using randomized parallel control method, 110 inpatients and outpatients were randomly divided into two groups randomly according to the lot number sequence of visiting doctor. Control group, 55 cases of vinpocetine, began 20mg + 0.5% glucose solution 500m L, 1 / d, slow intravenous infusion, after the disease can be increased to 30mg / d. The treatment group 55 cases gastrodin injection 150mg / time, 2 times / d, intramuscular injection; western medicine treatment with the control group. Continuous treatment 14d for a course of treatment. Clinical symptoms, vertebral artery blood flow velocity, basilar artery blood flow velocity, adverse reactions were observed. Continuous treatment of 2 courses to determine the efficacy. [Results] In the treatment group, 22 cases were cured, 19 cases were markedly effective, 11 cases were effective and 3 cases were ineffective. The total effective rate was 94.55%. The control group cured 19 cases, markedly effective in 17 cases, effective in 9 cases, ineffective in 10 cases, the total effective rate was 81.82%. The treatment group was better than the control group (P <0.05). The velocity of vertebral artery and basilar artery was improved in both groups (P <0.05, P <0.01), and the improvement in the treatment group was better than that in the control group (P <0.01). [Conclusion] Gastrodin injection combined with vinpocetine in treatment of Vertebrobasilar insufficiency vertigo has satisfactory curative effect and no serious adverse reactions, which is worth to be popularized.