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随着抗菌素和肾上腺皮质类固醇激素的广泛应用,眼部病毒性感染亦日愈增多,尤以单纯疱疹性角膜炎(Herpes simplex keratitis)为最多。本病的临床表现较特殊,治疗亦较难,是眼科医生感到棘手的疾病之一。现仅复习部分文献,结合作者的临床实践体会,综述如下: 病原体早在1817年Hornet就描述过单纯性角膜疱疹的临床症状,但直到1912年Grüter才发现其病原体为单纯疱疹病毒(Virus of herpes simplex),并成功地进行了实验性的兔和盲人角膜的感染。疱疹病毒的大小,平均直径约为100~
With the widespread use of antibiotics and adrenal corticosteroids, ocular viral infections are also increasing, especially Herpes simplex keratitis. The clinical manifestations of the disease is rather special, the treatment is also more difficult, is one of the ophthalmologist feel thorny diseases. Now review only some of the literature, combined with the author’s clinical experience, are summarized as follows: Pathogens Hornet described the clinical symptoms of simple herpes as early as 1817, but until 1912 Grüter only found that the pathogen is herpes simplex virus (Virus of herpes simplex) and successfully performed experimental rabbit and blind corneal infection. Herpes virus size, the average diameter of about 100 ~