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前言 L—threo—1—对硝基苯基—2—氨基—1,3—丙二醇(以下简称右旋氨基物)是在氯霉素生产过程中拆分一步所得到的副产物。它的二氯乙酰化物无抗菌活性。如何利用这部分几乎占总量一半的副产物来增加总收率是具有重大经济意义的课题。目前生产中所采用的方法是用酸性高锰酸钾将右旋氨基物分子中的仲醇基氧化为羰基,因而去掉
Introduction L-threo-1-p-nitrophenyl-2-amino-1,3-propanediol (hereinafter referred to as D-amino) is a byproduct obtained after one step of chloramphenicol production. Its dichloroacetylates have no antibacterial activity. It is of great economic significance to use this part of the total byproduct to increase the total yield. The current method of production is the use of acid potassium permanganate dextrinoide molecule secondary alcohol group is oxidized to carbonyl, thus removing