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目的:探讨原发性肝癌患者血清IL-6、IL-8、TNF-α含量与肝损程度的相关性。方法:40例原发性肝癌患者及50例肝硬化患者,检测血清IL-6、IL-8、TNF-α水平。结果:血清中IL-6、IL-8、TNF-α水平,随肝损程度加重,血清的IL-6、IL-8、TNF-α含量随之增加。结论:原发性肝癌患者血清IL-6、IL-8、TNF-α水平与肝脏损伤程度密切相关,是判定预后的重要指标。
Objective: To investigate the correlation between serum levels of IL-6, IL-8 and TNF-α and the degree of liver damage in patients with primary liver cancer. Methods: Forty patients with primary liver cancer and 50 patients with cirrhosis were enrolled in this study. Serum levels of IL-6, IL-8 and TNF-α were measured. Results: The levels of IL-6, IL-8 and TNF-α in serum increased with the severity of liver damage. Conclusion: The levels of serum IL-6, IL-8 and TNF-α in patients with primary liver cancer are closely related to the degree of liver injury, which is an important index to judge the prognosis.