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目的:评价氧氟沙星滴眼剂的临床疗效及其安全性。方法:眼疾病病人验证组121例(男性63例,100只眼,女性58例,88只眼,年龄30a±s21a),用伊犁哈萨克自治州友谊医院研制的0.3%氧氟沙星滴眼剂。对照组39例(男性15例,22只眼,女性24例,35只眼,年龄35a±10a),用日本参天制药株式会社生产的0.3%氧氟沙星滴眼剂。每次均1滴(约0.2mL),tid。治疗开始后d4,d7及d14复诊。结果:验证组细菌性眼疾病总显效率为71.3%,对照组为32%(P<0.01)。结论:伊犁哈萨克自治州友谊医院研制的氧氟沙星滴眼剂对细菌性眼疾有明显治疗作用。
Objective: To evaluate the clinical efficacy and safety of ofloxacin eye drops. Methods: 121 patients (63 males, 100 eyes, 58 females, 88 eyes, age 30a ± s21a) were enrolled in the validation group of patients with ocular diseases. Eye drops of 0.3% of ofloxacin developed by Friendship Hospital of Ili Kazakh Autonomous Prefecture Agent. The control group of 39 patients (15 males and 22 females, 24 females, 35 eyes, age 35a ± 10a), with Japan’s Pharmaceutical Co., Ltd. 0.3% ofloxacin eye drops. 1 drop each time (about 0.2 mL), tid. D4, d7 and d14 follow-up after the start of treatment. Results: The total effective rate of bacterial eye diseases was 71.3% in the test group and 32% in the control group (P <0.01). Conclusion: Ofloxacin eye drops developed by the Friendship Hospital of Ili Kazakh Autonomous Prefecture have a significant therapeutic effect on bacterial eye diseases.