已知在三磷酸腺苷(ATP)耗尽时,年青红细胞要比老的红细胞形成更多的不同类型的泡囊。本文作者研究了正常人红细胞在体外老化过程中这些细胞碎片的作用。标本系取自新鲜静脉血,肝素抗凝,用Sayder等1983年介绍的纤维素柱过滤的方法除去白细胞和血小板,然后将洗涤过的红细胞用Percoll/Hypaque梯度分离液把红细胞分为6层。作者将血红蛋白浓度(MCHC)低于33g/dl和平均有15％网织红细胞的 It is known that young red blood cells form more different types of vesicles than old red blood cells when adenosine triphosphate (ATP) is depleted. The authors studied the role of these cell debris in normal human erythrocytes during in vitro aging. Specimens were obtained from fresh venous blood and anticoagulated with heparin. Leukocytes and platelets were removed by cellulose filtration as described by Sayder et al. In 1983. The washed red blood cells were then separated into six layers using a Percoll / Hypaque gradient. The authors have a hemoglobin concentration (MCHC) of less than 33 g / dl and an average of 15% reticulocyte