青霉素类抗生素,一般认为其毒性小,既有作用于革兰氏阳性细菌的制剂,又有适用于革兰氏阴性细菌的制剂,在内科、外科、小儿科及传染病的临床上青霉素类抗生素应用广泛,且常常作为抗感染或预防感染的首选药物。近年来国外报告青霉素类抗生素,引起间质性肾炎的报告已不少见,因此在临床使用中应引起警惕。一、能诱发间质性肾炎的青霉素类药物有以下几种 1.青霉素 Penicillins antibiotics, generally considered to be less toxic, both for Gram-positive bacteria in the preparation, but also for Gram-negative bacteria in the preparation of clinical, penicillin antibiotics in the internal medicine, surgery, pediatrics and infectious diseases Widely used as a drug of choice for anti-infective or infection prevention. In recent years, reports of penicillin antibiotics in foreign countries, causing interstitial nephritis have been rare, so should be vigilant in clinical use. First, can induce interstitial nephritis penicillin drugs have the following 1 penicillin