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性激素和妇科恶性肿瘤的发生有无关系是多年来学者深入探索的问题,今就有关问题概述如下: 一、雌激素与子宫内膜癌自从Allen和Doisy(1923)提出子宫内膜癌的发生可能和雌激素有关以来,经过许多学者的研究,目前多数学者认为子宫内膜癌的发生可能与雌酮有关。但究竟何种雌激素有致癌作用,尚待进一步研究。 (一)子宫内膜癌患者雌激素的来源 1.来自性腺的内源性雌激素妇女正常月经周
The relationship between sex hormones and gynecologic malignancies has been explored by scholars for many years. Nowadays, the related issues are summarized as follows: 1. Estrogen and endometrial cancer Since the advent of endometrial cancer, Allen and Doisy (1923) And estrogen related, after many scholars study, at present most scholars believe that the occurrence of endometrial cancer may be associated with estrone. However, what kind of estrogen carcinogenic effect, yet to be further studied. (A) the source of estrogen in patients with endometrial cancer 1. Endogenous estrogen from the gonadal women normal menstrual weeks