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我院自1983年9月以来对14例膀胱癌用卡介苗(BCG)膀胱内灌注治疗和预防取得良好效果。现小结如下。一、方法患者行BCG治疗前作1:2000OT皮肤试验和摄胸片。用BCG为巴斯德菌株的丹麦Ⅱ菌种(上海生物制品研究所制剂),每毫升含菌75mg(3×10~8活菌),取6×10~8活菌加4℃生理盐水60ml稀释注入膀胱,每15分钟改变体位,前、后、左及右,保留2小时。每周1次,共6次,半月1次×6,1月一次×24。若治疗过程中复发则重复以上治疗。灌注前后和过程中定期测定RBC、WBC,BPC、血BUN、Cr、AKP、SGOT以观察BCG治疗的副作用。每3个月作OT皮肤试验、尿细胞学和膀胱镜检查及膀胱多处活检(原肿瘤
In our hospital since September 1983 14 cases of bladder cancer with intra-BCG intravesical instillation and prevention achieved good results. Now summarized as follows. First, the method of patients before BCG treatment for 1: 2000OT skin test and radiography. With BCG Pasteur strain Denmark Ⅱ strain (Shanghai Institute of Biological Products), per milliliter containing bacteria 75mg (3 × 10 8 live bacteria), take 6 × 10 8 live bacteria and 4 ℃ saline 60ml Dilute into the bladder, every 15 minutes to change position, before, after, left and right, for 2 hours. Once a week, a total of 6 times, a half months 1 × 6, January once × 24. If the recurrence of the treatment process is repeated above treatment. RBC, WBC, BPC, blood BUN, Cr, AKP and SGOT were measured regularly before and after perfusion to observe the side effects of BCG therapy. Every 3 months for OT skin test, urinary cytology and cystoscopy and bladder multiple biopsy (the original tumor