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I型胰岛素样生长因子受体(IGF-1R)是肿瘤治疗特别是基因治疗的良好靶体.本研究首先应用免疫细胞化学SP法检测IGF-1R在体外培养的胰腺癌细胞系SW1990上的表达,然后合成针对IGF-1R的反义寡核苷酸(ASON).所有反
Type I insulin-like growth factor receptor (IGF-1R) is a good target for tumor therapy, especially gene therapy. In this study, immunocytochemical SP method was used to detect the expression of IGF-1R on pancreatic cancer cell line SW1990 cultured in vitro. And then synthesize antisense oligonucleotides (ASON) against IGF-1R.