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目的:探讨18F-脱氧葡萄糖(FDG)PET延迟显像在原发性肺癌诊断中的价值。方法:对36例原发性肺癌患者分别进行18F-FDG PET早期头部——盆腔显像和注射后3h胸部延迟显像,测定2次显像病灶的标准摄取值(SUV),并计算18F-FDG的储留指数(RI)。结果:原发性肺癌的延迟显像SUV明显高于早期显像SUV(P<0.01);以早期显像SUV>2.5作为标准,原发性肺癌诊断的灵敏度、特异性、准确性分别为80.3%、72.7%、78.6%;以RI>20%作为标准,原发性肺癌诊断的灵敏度、特异性、准确性分别为82.8%、77.9%、80.3%;结合以上2项标准,原发性肺癌诊断灵敏度、特异性、准确性分别为90.0%、80.0%和86.7%。结论:18F-FDG PET延迟显像有助于原发性肺癌的诊断,结合应用SUV及RI2项指标可提高诊断准确率。
Objective: To investigate the value of 18F-deoxyglucose (FDG) PET delayed imaging in the diagnosis of primary lung cancer. Methods: Thirty-six patients with primary lung cancer underwent early head-pelvic imaging of 18F-FDG PET and delayed thoracic imaging at 3h after injection. The standard imaging values (SUVs) of secondary imaging lesions were measured and 18F The storage index (RI) of FDG. Results: The delayed imaging SUV of primary lung cancer was significantly higher than that of early imaging SUV (P <0.01). The sensitivity, specificity and accuracy of early imaging SUV> 2.5 were 80.3 %, 72.7% and 78.6%, respectively. The sensitivity, specificity and accuracy of diagnosis of primary lung cancer were 82.8%, 77.9% and 80.3%, respectively, with RI> 20% The diagnostic sensitivity, specificity and accuracy were 90.0%, 80.0% and 86.7% respectively. Conclusion: 18F-FDG PET delayed imaging is helpful for the diagnosis of primary lung cancer. The combination of SUV and RI2 can improve the diagnostic accuracy.