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目的:研究在急性心肌梗塞患者使用溶栓疗法来降低其死亡率与并发症。方法:27例急性心肌梗塞在首次症状发作12小时内,采用静滴日产尿激酶150万U(30分钟)。其疗效与采用常规治疗方案的27 例急性心肌梗塞作比较。结果:78％(21/27)经溶栓冶疗的患者呈现再灌注成功,2例(7%)并发严重心衰,对照者为8例(30%):5周后的死亡率冶疗组为7%,对照组为30%(P<0.01)。结论:在急性心肌梗塞病人采用静脉溶栓疗效可有效地降低死亡率与并发症。
PURPOSE: To study the use of thrombolytic therapy in patients with acute myocardial infarction to reduce their mortality and complications. METHODS: Twenty-seven patients with acute myocardial infarction received intravenous infusion of 1.5 million U of urokinase (30 minutes) during the first 12 hours of onset of symptoms. Its efficacy compared with 27 cases of acute myocardial infarction with conventional treatment. RESULTS: Seventy-eight percent (21/27) patients underwent thrombolysis showed successful reperfusion, 2 (7%) developed severe heart failure compared with 8 (30%) controls: mortality after 5 weeks treatment Group 7%, control group 30% (P <0.01). Conclusion: The use of intravenous thrombolytic therapy in patients with acute myocardial infarction can effectively reduce the mortality and complications.