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目的 :对“肠安康”进行小鼠灌胃造成的急性毒性试验 ,观察其安全性 ,为临床研究提供依据。方法 :以“肠安康”最大浓度、最大体积对小鼠灌胃 ,测定其1日最大给药量。结果 :小鼠 1日最大给药量为 4.5g,相当于成人临床日用量的 375倍。结论 :“肠安康”较为安全 ,可供临床研究试用
Objective : To evaluate the acute toxicity caused by intragastric administration of “Intestinal Ankang” and observe the safety of it, so as to provide the basis for clinical research. METHODS: The mice were intragastrically administered with the maximum concentration and maximum volume of “Intestinal Ankang” and the maximum daily dose was measured. RESULTS: The maximum daily dose of mice was 4.5 g, which was equivalent to 375 times of the daily dosage of adults. Conclusion: “Intestinal health” is safer and can be used in clinical trials