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本品为白色结晶性粉末,味微苦,易溶于水,微溶于醇,不溶于丙酮和醋酸乙酯。阿司匹林在临床上应用已有八十余年之久,因其疗效甚佳,毒性较低,至今仍为具有代表性的解热镇痛药物。由于它微溶于水,只能供口服使用,又因对胃肠道刺激性较大,甚至导致胃肠出血,有些病人不能耐受。为了减少其副作用,提高疗效,扩大使用范围,国内外均在研究将阿司匹林制成注射用的剂型。近十年来国外大力开展阿司匹林与碱性氨基酸制成可溶
This product is white crystalline powder, slightly bitter taste, soluble in water, slightly soluble in alcohol, insoluble in acetone and ethyl acetate. Aspirin has been used clinically for more than 80 years because of its excellent curative effect and low toxicity. It is still a representative antipyretic and analgesic drug. Because it is slightly soluble in water, only for oral use, but also because of gastrointestinal irritation, and even lead to gastrointestinal bleeding, some patients can not tolerate. In order to reduce its side effects, improve efficacy and expand the scope of use, both at home and abroad are studying the aspirin made of injection formulations. Nearly a decade abroad, aspirin and basic amino acid made soluble