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本研究应用放射免疫分析技术,检测胃液癌胚抗原(CEA)和甲胎蛋白(AFP),研究二者和癌前疾病的关系。实践结果表明:胃十二指肠溃疡病组与慢性萎缩性胃炎组间无显著差异,胃与十二指肠溃疡组和慢性浅表性胃炎也无显著差异,而慢性萎缩性胃炎和慢性浅表胃炎有显著差异,表明溃疡病与萎缩性胃炎既和胃良性病有一定联系,又有一定差异,具有癌变的可能,只是接近癌肿的程度不同,胃十二指肠溃疡更接近于胃良性病,萎缩性胃炎更接近于胃癌。本文支持胃溃疡及萎缩性胃炎为癌前疾病的意见。
In this study, radioimmunoassay was used to detect carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) in gastric juice, and the relationship between them and precancerous lesions was studied. The practical results showed that there was no significant difference between the gastroduodenal ulcer group and the chronic atrophic gastritis group, and there was no significant difference between the gastroduodenal ulcer group and the chronic superficial gastritis, but chronic atrophic gastritis and chronic shallowness. Table gastritis has a significant difference, indicating that ulcer disease and atrophic gastritis are not only related to benign disease in the stomach, but also have some differences, with the possibility of cancer, but the degree of close to cancer is different, gastric and duodenal ulcers are closer to the stomach Benign disease, atrophic gastritis is closer to gastric cancer. This article supports the opinion that gastric ulcer and atrophic gastritis are precancerous diseases.