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糖皮质激素如氢化可的松、强的松、强的松龙、地塞米松等早已广泛应用于临床,使用不当常可导致药源性疾病。近年来我们陆续见到因糖皮质激素引起的以进行性殷骨头无菌性坏死为主的髋关节病3例,结合复习资料报告如下。病例介绍例1 女,50岁,因患天泡疮于1970年7月就诊于某院皮肤科,给予服可的松(60—70毫克/日)共45天,以后改为强的松30毫克/日共80天。后因旧病重发加大剂量60—80毫克/日共120天后,改为强的松龙30毫克/日约8个月。至1973年5月,即开始服激素后3年,总剂量达到19600毫克,患者感四肢
Glucocorticoids such as hydrocortisone, prednisone, prednisolone, dexamethasone, etc. have long been widely used in clinical practice, inappropriate use can often lead to drug-induced diseases. In recent years, we have gradually seen due to glucocorticoid induced progressive osteonecrosis of the main osteoarthritis of the hip in 3 cases, combined with the review report is as follows. Case introduction Example 1 Female, 50 years old, because of the day of the sox Curing in July 1970 in a hospital dermatology, given cortisone (60-70 mg / day) a total of 45 days later changed to prednisone 30 Mg / day for a total of 80 days. After the old disease due to increased doses of 60-80 mg / day total of 120 days, to prednisolone 30 mg / day about 8 months. By May 1973, 3 years after starting hormone therapy, the total dose reached 19,600 mg and the patient felt limbs