食管贲门粘膜撕裂症(Mallory-Weiss综合征)系因反复剧烈的呕吐、干呕及腹内压力增高引起食管、胃连接处的粘膜撕裂,同时伴有上消化道出血的疾病。近年来,由于纤维内窥镜的广泛应用,尤其作为上消化道出血急诊检查方法以来,本症发现率有所提高。我院1975～1978年经急诊内窥镜证实的有5例,现将资料完整的4例报告如下。病例报告【例1】张××,男性,47岁。因呕血2小时急诊入院。发病前病人因牙痛自服吗啡2粒后,出现呕吐大量酸水,伴头晕、心慌、出汗,继而呕血约1,000毫升。以往有间歇性中上腹痛19年。体格检查:血压140/96毫米汞柱,脉搏84/分,体温36.5℃,一般情况好,神志清楚。心肺正常。剑突下偏右压痛,肠鸣活跃。实验室检查:血红蛋白13.2克%,白细胞4,800/立方 Esophageal and gastric mucosal tear (Mallory-Weiss syndrome) is due to repeated severe vomiting, retching and intra-abdominal pressure caused by esophageal and gastric junction mucosal tear, accompanied by upper gastrointestinal bleeding disease. In recent years, due to the widespread use of fiber endoscopy, especially as an emergency upper gastrointestinal bleeding examination method, the detection rate of this disease has increased. Our hospital from 1975 to 1978 confirmed by emergency endoscopy in 5 cases, now the data are complete in 4 cases reported as follows. Case Report 【Example 1】 Zhang × ×, male, 47 years old. Due to hematemesis 2 hours emergency admission. Before the onset of the patient due to toothache spontaneously morphine 2 tablets, vomiting large amounts of sour water, with dizziness, palpitation, sweating, and then vomiting about 1,000 ml. In the past there is intermittent upper abdominal pain for 19 years. Physical examination: blood pressure 140/96 mm Hg, pulse 84 / min, temperature 36.5 ℃, the general situation is good, conscious. Cardiopulmonary normal. Xiphoid right tenderness, bowel sounds active. Laboratory tests: hemoglobin 13.2%, white blood cells 4,800 / cubic