恶性胸水多有肿瘤细胞浸润胸膜、淋巴结转移或播散及肿瘤增加体循环静脉压所致 ,单纯全身化疗副作用大且不易控制 ,局部抽液疗效欠佳 ,胸腔给药多有效 ,我科于 1994 - 0 6～ 2 0 0 0 - 0 2用丝裂霉素 5-Ｆｕ联合胸腔内给药方法治疗恶性胸水 2 9例 ,总结如下。1　对象和方法对象 Malignant pleural effusions are mostly caused by tumor cell infiltration of the pleura, lymph node metastasis or dissemination, and increased circulatory venous pressure caused by tumors. Systemic chemotherapy alone has large side effects and is not easy to control. The efficacy of local fluid pumping is poor, and pleural administration is more effective. Treatment of malignant pleural effusion with mitomycin-5-Fu in combination with intrapleural administration of 0 6 to 2 0 0 0 - 0 2 was summarized as follows. 1 Object and Method Objects