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目的探讨急性心肌梗死与载脂蛋白的关系。方法测定48例急诊科就诊的急性心肌梗死(acute myocardial infarction,AMI)患者血清载脂蛋白B水平,并与25例健康对照组的血清载脂蛋白B进行比较,采取统计方法进行显著性检验。结果与健康对照组比较,AMI组载脂蛋白B明显升高,差异有统计学意义(P<0.01)。结论急性心肌梗死与载脂蛋白B(apoprotein B,APOB)关系密切,这可能与APOB增高,低密度脂蛋白升高易导致冠状动脉粥样硬化,从而使心肌梗死的危险性增加有关。
Objective To investigate the relationship between apolipoprotein and acute myocardial infarction. Methods Serum apolipoprotein B levels were measured in 48 patients with acute myocardial infarction (AMI) treated in the emergency department and compared with serum apolipoprotein B levels in 25 healthy controls. Statistical analysis was performed for significance. Results Compared with the healthy control group, the apolipoprotein B in AMI group was significantly increased (P <0.01). Conclusions Acute myocardial infarction is closely related to apoprotein B (APOB), which may be related to the increase of APOB and the rise of low density lipoprotein, leading to coronary atherosclerosis and the increased risk of myocardial infarction.