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目的 :研究腹腔镜直肠癌根治术对患者胃肠功能及疼痛状态相关血清指标的表达影响。方法 :选取2011年6月~2015年5月于本院进行根治术治疗的62例直肠癌患者为研究对象,将62例手术患者随机分为对照组和观察组,对照组的31例患者以开放式手术进行治疗,观察组的31例患者则以腹腔镜手术进行治疗,然后将两组患者术前及术后不同时间的肛肠动力学指标、胃肠激素及疼痛状态相关血清指标进行比较。结果 :术前两组患者的肛肠动力学指标、胃肠激素及疼痛状态相关血清指标均无显著性差异,而术后1d、7d及14d观察组的胃肠激素及疼痛指标均好于对照组,而术后2周、4周及8周观察组的肛肠动力学指标也好于对照组,均有显著性差异。结论 :腹腔镜直肠癌根治术对患者胃肠功能的不良影响及疼痛状态控制效果相对更好,因此更为适用于直肠癌手术治疗的患者。
Objective: To study the effect of laparoscopic radical mastectomy on the expression of serum markers related to gastrointestinal function and pain state in patients. Methods: Sixty-two patients with rectal cancer who underwent radical operation in our hospital from June 2011 to May 2015 were selected as study objects. Sixty-two patients with surgery were randomly divided into control group and observation group. 31 patients in control group Open surgery was performed. The 31 patients in the observation group were treated by laparoscopic surgery. The anorectal motility, gastrointestinal hormones and pain-related serum indexes were compared between the two groups before and after surgery. Results: There was no significant difference in anorectal motility, gastrointestinal hormones and pain-related serum indexes between the two groups before surgery, while the indexes of gut hormone and pain in the observation group at 1d, 7d and 14d after operation were better than those in the control group , But the indexes of anorectal motility in observation group at 2 weeks, 4 weeks and 8 weeks after surgery were also better than those in control group, with significant differences. Conclusions: Laparoscopic radical resection of rectal cancer has a better control effect on gastrointestinal function and pain state in patients, so it is more suitable for patients undergoing rectal cancer surgery.