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我院曾收治一例多发性骨髓瘤并脑膜骨髓瘤病人,在治疗中误将200mg甲氨喋呤注入鞘内引起严重反应,现报道如下: 病例摘要患者女性,37岁。主因头痛眼胀伴眼球外突10个月,于1988年3月17日入院。缘于10月前无诱因的头部持续性胀痛。转颈时加重,双眼球渐外突,四肢无力,不能劳动。有间断性恶心呕吐(非喷射性),吐后头痛减轻。近3月出现视物不清,耳鸣,耳聋。他院按“神经性头痛”治疗效果不佳遂来就诊收住院。病后食欲好,二便正常。既往健康,家族中无特殊记述。查体:T36℃,P86次/分,BP120/80mmHg,发育正常,营养中等,神清合作。浅淋
A hospital with multiple myeloma and meningioma was admitted to our hospital. In the treatment, mistreatment of 200 mg methotrexate into the sheath caused serious reaction. The report is as follows: Case Summary Female patient, 37 years old. Mainly due to headache, eye swelling with eyeball protrusion 10 months, March 17, 1988 admission. Due to unprovoked head of persistent pain in October. Rotating neck aggravate, his eyes gradually protruding, limbs weakness, can not work. There is intermittent nausea and vomiting (non-jet), headache relieved after vomiting. Nearly 3 months apparent blurred vision, tinnitus, deafness. His hospital by “neurological headache,” poor treatment then come to the hospital for admission. Good appetite after illness, two will be normal. Past health, no special account of the family. Physical examination: T36 ℃, P86 times / min, BP120 / 80mmHg, normal development, moderate nutrition, Shen Qing cooperation. Shallow shower