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目的:探讨海南州地区妇女宫颈病变的现状及临床意义,为宫颈癌的防治提供依据。方法:查阅2009年9月—2013年12月我地区4 865例(20～70)岁因各种妇科疾病就诊于我院妇科门诊行宫颈液基细胞学检查(TCT)的妇女,采用妇科常规检查、TCT检查进行宫颈癌筛查,用TBS-2001诊断系统进行分析,做出诊断。对细胞学异常患者,行阴道镜下取活检。结果:宫颈细胞学异常者408例,检出率为8.39%。各年龄组患病情况之间有差异。上皮内病变高发年龄组为(30～39)岁。高级别CIN高发年龄组为(40～49)岁,宫颈癌的高发年龄组为(50～70)岁。上皮内病变(CIN)检出率25.90‰,宫颈癌检出率3.49‰。经组织学活检确诊为CIN者109例,宫颈鳞癌20例。CIN检出率22.40‰,宫颈癌检出率4.11‰。结论:在宫颈癌筛查中应用TCT检查,能够大幅度提高宫颈疾病检出的阳性率,提早发现癌前病变,早期治疗,以降低宫颈癌的发生。
Objective: To investigate the status and clinical significance of cervical lesions in women in Hainan Province, and to provide evidence for the prevention and treatment of cervical cancer. Methods: From September 2009 to December 2013, 4,865 women (20-70 years old) with cervical gynecological cytology (TCT) who visited our gynecology clinic for various gynecological diseases in our hospital from September 2009 to December 2013 were enrolled in this study. Check, TCT screening cervical cancer screening, with TBS-2001 diagnostic system for analysis, make a diagnosis. Abnormal cytology patients underwent colposcopy biopsy. Results: 408 cases of cervical cytology abnormalities, the detection rate was 8.39%. There are differences between the prevalence of various age groups. High incidence of intraepithelial lesions in the age group (30 to 39) years old. High-grade CIN high incidence of age group (40 to 49) years of age, high incidence of cervical cancer group (50 to 70) years of age. Intraepithelial lesion (CIN) detection rate of 25.90 ‰, cervical cancer detection rate of 3.49 ‰. 109 cases were confirmed by histological biopsy CIN, cervical squamous cell carcinoma in 20 cases. CIN detection rate of 22.40 ‰, cervical cancer detection rate of 4.11 ‰. Conclusion: The application of TCT in cervical cancer screening can greatly improve the positive rate of cervical disease detected early detection of precancerous lesions, early treatment to reduce the incidence of cervical cancer.