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肾综合症出血热(HFRS)并多发性神经炎者比较少见。我院1988年3月至1998年3月人院治疗的3846例HFRS患者中,48例(1.25％)并多发性神经炎。现报告如下。1 临床资料1.1 一般资料 48例诊断和分型均符合1986年全国HFRS学术会议修订的标准,并经特异性血清证实。男36例,女12例,平均年龄38.6岁,重型4例,危重型44例。1.2 临床表现 多发性神经炎者发生于发热末期2例,少尿期24例,多尿期22例,平均在第(15.94±7.52)病日。1.2.1 脑神经受损 38例(占79％);面神经受损34例(占89％),单侧14例,双侧20例,表现为面部表情肌瘫痪,患侧额纹消失,眼裂开大,闭合不全,鼻唇沟平坦,口角下垂;其中3例伴有轻度的感觉障碍。听神经受损4例,表现为听力下降。
Hemorrhagic fever with renal syndrome (HFRS) and polyneuritis are rare. Among 3846 HFRS patients hospitalized from March 1988 to March 1998 in our hospital, 48 (1.25%) patients had multiple neuritis. The report is as follows. 1 Clinical data 1.1 General information 48 cases of diagnosis and typing are in line with the 1986 National HFRS academic conference revised standards, and confirmed by specific serum. There were 36 males and 12 females, with an average age of 38.6 years, 4 cases of severe type and 44 cases of critical type. 1.2 Clinical manifestations of polyneuritis occurred in the end of fever in 2 cases, 24 cases of oliguria, polyuria in 22 cases, averaging (15.94 ± 7.52) days. 1.2.1 Cerebral nerve damage in 38 cases (79%); facial nerve damage in 34 cases (89%), unilateral in 14 cases, bilateral in 20 cases, manifested as facial expression muscle paralysis, ipsilateral forehead pattern disappeared, the eye Large split, closed incomplete, nasolabial fold flat, mouth drooping; of which 3 cases accompanied by mild sensory disturbances. Auditory nerve damage in 4 cases, manifested as hearing loss.