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应用ＲＩＡ法检测了非甲状腺疾病的慢性肝病１１０例，按肝功能称，含Ｂ级肝３６例，Ｃ级肝４０例，肝癌３４例和正常对照组３１例的血清甲状腺激素。结果显示：慢性肝病患者的血清Ｔ３、ＦＴ３值下降和ｒＴ３值升高，均较正常人有非常显著差异（Ｐ＜０．０１）；且Ｃ级肝和肝癌的大部分患者出现了低Ｔ３血症，发生率为７７．５％（３０／４０）和７６．４％（２６／３４）与正常人、Ｂ级肝比较均有非常显著差异（Ｐ＜０．０１）。肝癌和Ｂ级肝的部分患者还同时出现高Ｔ４血症，发生率分别为３３．２％（１２／３４）和３６．１％（１３／３６），该两组无显著差异。肝癌组有２例同时出现低Ｔ３、Ｔ４血症，并在两周内死亡。可见，测定肝病患者的血清甲状腺激素，从一个侧面可反映其肝功能损害程度，对其诊断、治疗和预后都有临床参考意义。
RIA was used to detect 110 cases of non-thyroid disease chronic liver disease, according to liver function, including 36 cases of grade B liver, 40 cases of grade C liver, 34 cases of liver cancer and normal control group, 31 cases of serum thyroid hormone. The results showed that serum T3, FT3 decreased and rT3 increased in patients with chronic liver disease compared with normal people (P <0.01), and most patients with grade C and HCC developed low T3 blood The incidence rates were 77.5% (30/40) and 76.4% (26/34) respectively. There was a significant difference (P <0.01) between the two groups. Some patients with hepatocellular carcinoma and grade B liver also had hyper T4 disease, the incidence rates were 33.2% (12/34) and 36.1% (13/36) respectively. There was no significant difference between the two groups. Two patients in the HCC group also had hypo T3, T4 hyperlipidemia and died within two weeks. Visible, the determination of serum thyroid hormone in patients with liver disease, from one side can reflect the degree of liver damage, its diagnosis, treatment and prognosis have clinical significance.