论文部分内容阅读
为探讨高海拔地区慢性呼吸性酸中毒肾代偿范围和限度,本文总结了一定条件下的325例次肺心病慢性呼酸的酸硷、血气资料,其中HCO_3、BE和[H ̄+]与PaCO_2呈非常显著的直线相关;在一定范围内PaCO_2每升高1kPa、HCO_3约升高3.5mmol/L肾脏对PaCO_2的最大代偿限度为8kPa(60mmHg)。这些均与平原地区的文献资料基本吻合。[H] ̄+随PaCO_2的增加而升高,但升高的幅度依次递增,表现了肾脏对慢性高碳酸血症代偿后酸硷反应的规律。本资料经数理统计,提出了HCO_3、BE和[H ̄+]与PaCO_2的回归方程、95%可信限范围及慢性呼酸代偿预计公式,这对于判断单纯性慢性呼酸还是复和性酸硷紊乱具有一定应用价值。
In order to explore the range and limit of renal decompensation for chronic respiratory acidosis in high altitude area, 325 cases of chronic pulmonary acidosis and pH value were summarized under certain conditions. HCO3, BE, [H ~ +] and PaCO_2 showed a very significant linear correlation; within a certain range of PaCO_2 increased 1kPa, HCO_3 increased about 3.5mmol / L PaCO_2 kidney maximum compensation limit of 8kPa (60mmHg). These are basically consistent with the literature in the plains. [H] ¯ + increased with the increase of PaCO_2, but the increasing amplitude increased gradually, which showed the regularity of renal reaction to compensatory acid-base after chronic hypercapnia. The data through mathematical statistics, proposed HCO_3, BE and [H ~ +] and PaCO_2 regression equation, 95% confidence limits and chronic acidosis compensation formula, which for the judgment of simple chronic acidosis or complex Acid alkali disorders have a certain application value.