该研究对普伐他汀长期干预缺血性疾病(longterm intervention with pravastatin in ischaemic disease,LIPID)临床研究中的受试者进行长期随访,评估他汀类药物治疗对全因死亡、特定病因死亡和癌症发生率的长期影响。方法和结果:LIPID研究最初纳入9014例先前患冠状动脉性心脏病(coronary heart disease,CHD)的患者,比较使用普伐他汀和安慰剂治疗6年的疗效。双盲期之后,所有患者接受开放标签他 This study conducted long-term follow-up of participants in the pravastatin long-term intervention with pravastatin in ischaemic disease (LIPID) clinical trial to assess the effects of statin therapy on all-cause, specific cause of death and cancer The long-term impact of the rate. Methods and Results: The LIPID study initially included 9014 patients previously diagnosed with coronary heart disease (CHD) and compared their efficacy over 6 years with pravastatin and placebo. After the double-blind period, all patients accept the open label him