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目的:观察在常规药物基础上加用稳心颗粒联合倍他乐克治疗冠心病心律失常的临床效果。方法:选择68例冠心病心律失常患者为研究对象,随机分为观察组和对照组各34例,对照组使用常规治疗配合倍他乐克治疗,观察组在对照组基础上加稳心颗粒治疗,2组均用药4周。对2组患者疗效进行分析,观察治疗前后心功能与血液流变学的变化。结果:总有效率观察组为91.18%,对照组为70.59%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组心排出量(CO)、心脏指数(CI)、射血分数(EF)均治疗前升高(P<0.01),观察组各指标值均高于对照组(P<0.01)。2组全血黏度(低切)、全血黏度(高切)、血浆黏度、纤维蛋白原均较治疗前降低(P<0.01),观察组各项指标值均低于对照组(P<0.01)。结论:在常规药物基础上加用稳心颗粒联合倍他乐克治疗冠心病心律失常疗效确切,可有效改善心功能,缓解症状。
Objective: To observe the clinical effects of adding Wenxin granule combined with Betaloc on the basis of conventional drugs in the treatment of coronary heart disease. Methods: Sixty-eight patients with coronary heart disease and arrhythmia were randomly divided into observation group (34 cases) and control group (34 cases). The control group was treated with metoprolol. The observation group was treated with Wenxin Granule , Two groups were medication for 4 weeks. The efficacy of two groups of patients were analyzed, before and after treatment to observe changes in cardiac function and hemorheology. Results: The total effective rate was 91.18% in the observation group and 70.59% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the cardiac output (CO), cardiac index (CI) and ejection fraction (EF) of two groups were increased before treatment (P <0.01), and the indexes in the observation group were higher than those in the control group . The indexes of whole blood viscosity (low cut), whole blood viscosity (high cut), plasma viscosity and fibrinogen of two groups were lower than those before treatment (P <0.01) ). Conclusion: The combination of Wenxinkeli Granules and Betaloc on the basis of conventional drugs is effective in treating cardiac arrhythmia, which can effectively improve cardiac function and relieve symptoms.