【摘 要】
：
A pair of new tirucallane triterpenoid epimers,picraquassins M and N (1 and 2),were isolated from the stems of Picrasma quassioides (D.Don) Benn.Their structures were determined based on comprehensive spectroscopic and X-ray crystallographic analyses.In a
【机 构】
：
College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016,
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A pair of new tirucallane triterpenoid epimers,picraquassins M and N (1 and 2),were isolated from the stems of Picrasma quassioides (D.Don) Benn.Their structures were determined based on comprehensive spectroscopic and X-ray crystallographic analyses.In addition,their AChE inhibitory activity,cytotoxicity against five human tumour cell lines (SW480,MCF-7,HepG2,Hela,and PANC-1),and antimicrobial activity against two bacteria (Staphylococcus.aureus 209P and Escherichia coli ATCC0111) and two fungi (Candida albicans FIM709 and Aspergillus niger R330) were evaluated.
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