1964年Wilding等于1例高淀粉酶血症患者的血清中发现正常淀粉酶与球蛋白结合形成高分子物质。1967年Berk及同道发现3例病人有同样现象,并称之为“巨淀粉酶血疵”(Macroamylasaemia),他指出高淀粉酶血症并非都属胰腺淀粉酶增高。巨淀粉酶血 1964 Wilding equal to 1 case of patients with hypermylatic acidosis found in normal serum amylase and globulin binding to form high molecular weight substances. In 1967 Berk and his fellow humans found the same phenomenon in three patients and called it “Macroamylasaemia,” noting that hyper amylase was not always an increase in pancreatic amylase. Giant amylase blood