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目的分析以PCR为基础的人类乳头瘤病毒(HPV)检测在宫颈癌筛查中的应用价值。方法选取该院2014年3月-2016年4月收治的HPV感染引起的宫颈癌患者150例,随机将其分为研究组和对照组各75例。研究组使用PCR为基础的HPV检测方法,对照组使用常规组织病理学检查,比较2种检测方式患者的阳性率。结果研究组检测阳性率为94.67%(71/75)明显高于对照组的85.33%(64/75),差异有统计学意义(P<0.05)。结论PCR为基础的HPV检测技术在宫颈癌的筛查上具有简便快捷、高灵敏度、高特异性的特点,与传统检测方式相比准确性更高,故采用PCR检测技术可减少对宫颈癌患者的误漏诊情况,及时诊断有利于早期采取治疗措施,值得在临床上大力推广。
Objective To analyze the value of PCR-based human papillomavirus (HPV) detection in cervical cancer screening. Methods 150 patients with cervical cancer caused by HPV infection in our hospital from March 2014 to April 2016 were randomly divided into study group and control group with 75 cases each. The study group used PCR-based HPV test, while the control group used routine histopathology to compare the positive rate of the two test methods. Results The positive rate of the test group was 94.67% (71/75), which was significantly higher than that of the control group (85.33%, 64/75) (P <0.05). Conclusion The PCR-based HPV detection technique is simple, rapid, sensitive and specific in the screening of cervical cancer. Compared with the traditional detection methods, the PCR-based detection technique can reduce the risk of cervical cancer patients Misdiagnosis of the situation, timely diagnosis is conducive to early treatment, it is worth to clinically promote.