论文部分内容阅读
目的探讨丁苯酞、高压氧联合治疗急性脑梗死的疗效。方法将195例脑梗死患者随机分为常规治疗组(对照组)、丁苯酞治疗组(治疗组)和丁苯酞联合高压氧治疗组(联合治疗组),每组65例;常规治疗组给予抗血小板聚集、降脂稳定斑块、改善循环、脑细胞活化剂、调控血压、血糖等治疗;丁苯酞组给予常规治疗,同时给予丁苯酞胶囊200mg/次,3次/d,口服;丁苯酞联合高压氧治疗组给予常规治疗、丁苯酞胶囊200mg/次,3次/d,口服,共用20d,高压氧疗,1次/d,10次为1个疗程,共做2个疗程。对三组治疗前后行神经功能缺损评分和Bart He L指数(BI)进行日常生活活动能力(ADL)评分,探讨治疗急性脑梗死的疗效。结果治疗后21d联合治疗组神经功能缺损评分和Bart He L指数(BI)进行日常生活活动能力(ADL)评分明显优于对照组(P<0.01)。结论丁苯酞联合高压氧疗治疗急性脑梗死疗效满意。
Objective To investigate the efficacy of butylphthalide and hyperbaric oxygen in the treatment of acute cerebral infarction. Methods 195 patients with cerebral infarction were randomly divided into routine treatment group (control group), butylphthalide treatment group (treatment group) and butylphthalide combined hyperbaric oxygen treatment group (combination therapy group), 65 cases in each group; conventional treatment group Given anti-platelet aggregation, stable lipid-lowering plaque, improve circulation, brain cell activators, blood pressure control, blood glucose and other treatment; butylphthalide group given conventional treatment, while giving butylphthalide capsules 200mg / time, 3 times / d, ; Butylphthalide combined with hyperbaric oxygen treatment group given conventional treatment, butylphthalide capsules 200mg / time, 3 times / d, orally, shared 20d, hyperbaric oxygen therapy, 1 times / d, 10 times for a course of treatment, a total of 2 A course of treatment. The neurological impairment scores and Barthel’s index (BI) were measured before and after treatment to evaluate the activity of daily living (ADL) in three groups. The curative effect was evaluated in treating acute cerebral infarction. Results After 21 days of treatment, the neurological deficit score and Barthel index (BI) score of ADL in combination therapy group were significantly better than those in control group (P <0.01). Conclusion Butylphthalide combined with hyperbaric oxygen therapy is effective in treating acute cerebral infarction.