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抗病毒治疗人类免疫缺陷病毒(HIV)是艾滋病的病原体.在HIV复制周期中,逆转录酶催化的步骤(逆转录、循环与整合)和由逆转录活化调节的步骤(转录、剪接与转译)等环节是设计抗HIV药物的首选靶位.此外,HIV复制周期的起始阶段(吸附、穿透膜与脱壳)和终止阶段(装配、芽生与释放)也是药物攻击的重要靶位.应用单克隆抗体和类似于HIV包膜蛋白成分的一种寡肽(八肽)可阻断艾滋病病毒吸附到CD_4细胞受体上,并阻止其穿透细
Antiviral The human immunodeficiency virus (HIV) is the causative agent of AIDS and reverse transcriptase-catalyzed steps (reverse transcription, cycling and integration) and steps regulated by reverse transcriptional activation (transcription, splicing and translation) And other aspects of the design of anti-HIV drugs is the preferred target.In addition, HIV replication cycle in the initial stages (adsorption, penetration through the membrane and shelling) and the termination of the stage (assembly, budding and release) is also an important target for drug attacks. Monoclonal antibodies and an oligopeptide (octapeptide), similar to the HIV envelope protein component, block the adsorption of HIV on CD 4 cell receptors and prevent them from penetrating