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目的探讨~(131)Ⅰ治疗甲状腺功能亢进症的远期疗效。方法对北京中医药大学东直门医院2003-01-2006-12行放射性~(131)Ⅰ治疗的甲状腺功能亢进患者179例随访5a,评价远期临床治疗效果。结果 ~(131)Ⅰ治疗甲状腺功能亢进症5a随访治疗总有效率为91.46%,随访1a后发现甲状腺质量大患者出现甲低的概率相对较低;甲状腺吸碘率越高者甲减发生率越低。结论 131I治疗甲状腺功能亢进症远期疗效显著,是目前治疗甲状腺功能亢进症的有效方法。患者甲减的发生与患者甲状腺质量、甲状腺吸碘率具有相关性。
Objective To investigate the long-term effect of ~ (131) Ⅰ in the treatment of hyperthyroidism. Methods A total of 179 hyperthyroidism patients treated by Radioactive 131I Ⅰ in Dongzhimen Hospital of Beijing University of Chinese Medicine from January 2003 to December 2006 were followed up for 5 years to evaluate the long-term clinical effect. Results The total effective rate of follow-up treatment of ~ (131) Ⅰ in the treatment of hyperthyroidism was 91.46%. The low probability of hypothyroidism was found in patients with high thyroid mass after follow-up of 1a. The higher the rate of thyroid iodine uptake, the more the incidence of hypothyroidism low. Conclusion 131I treatment of hyperthyroidism long-term effect is significant, is currently an effective method of treatment of hyperthyroidism. The incidence of hypothyroidism in patients with thyroid quality, thyroid iodine uptake rate has relevance.