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目的探讨血液透析合并冠心病多支病变的老年肾衰竭患者外周血脂质水平。方法将128例行血液透析治疗、疑似冠心病、年龄超过60岁的慢性肾衰竭患者根据冠脉造影检查结果分为两组,血管病变不超过50%的患者纳入对照组(67例),存在多支病变的患者纳入实验组(61例),检测并比较两组患者透析治疗后外周血三酰甘油(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)、脂蛋白(a)[Lp(a)]的水平。结果实验组TG、TC、LDL、Lp(a)水平高于对照组,组间比较差异均有统计学意义(P<0.05)。结论脂质代谢紊乱是影响慢性肾衰竭持续血液透析治疗老年患者病变程度的重要因素。
Objective To investigate the peripheral blood lipid levels in elderly patients with renal failure undergoing hemodialysis combined with coronary artery disease. Methods A total of 128 patients with chronic renal failure who underwent hemodialysis, suspected coronary heart disease and over 60 years of age were divided into two groups based on the result of coronary angiography. Among those patients, no more than 50% of vascular lesions were included in the control group (67 cases) Patients with multi-vessel disease were included in the experimental group (61 cases). The levels of triglyceride (TG), total cholesterol (TC), low density lipoprotein (LDL), lipoprotein [Lp (a)] level. Results The levels of TG, TC, LDL and Lp (a) in the experimental group were significantly higher than those in the control group, with statistical significance (P <0.05). Conclusion The disorder of lipid metabolism is an important factor that affects the hemodialysis of chronic renal failure in the treatment of the elderly patients.