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低分子糖亦称寡聚糖,由2～10个单糖单元通过苷键结合而成,较之多糖具有独特的结构。低分子糖的生物活性,特别是抗肿瘤活性与其结构密切相关,已成为当今糖化学领域的研究热点。综述了寡聚糖的化学结构及其抗肿瘤的构效关系等相关研究新进展。并指出低分子糖作为抗肿瘤药物的研究方向。
Low molecular weight sugar, also known as oligosaccharides, from 2 to 10 monosaccharide units through glycosidic bond formed, compared with polysaccharide has a unique structure. The biological activity of low molecular sugar, especially its antitumor activity is closely related to its structure, which has become a research hotspot in the field of sugar chemistry today. Recent advances in the research on the chemical structure of oligosaccharides and their antitumor activity-activity relationship were reviewed. And pointed out that low molecular weight sugar as anti-tumor drug research.