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目的调查盐城地区肺结核患者耐药情况。方法采用比例法对534株痰培养阳性菌株进行药敏试验。结果 534株结核分枝杆菌的总耐药率为30.90%,耐多药率为13.48%;复治患者耐多药率明显高于初治患者的耐多药率(χ2=26.08,P<0.01)而单耐药率明显低于初治病人的耐药率(χ2=11.26,P<0.01)。结论要严格执行结核病控制策略,保证肺结核患者得到规范、有效的治疗管理,防止耐药菌株的产生和传播。
Objective To investigate the drug resistance of patients with pulmonary tuberculosis in Yancheng area. Methods 534 strains of sputum culture positive strains were susceptible test by proportional method. Results The total drug resistance rate of Mycobacterium tuberculosis in 534 strains was 30.90% and the multidrug resistance rate was 13.48%. The multidrug resistance rate of retreatment patients was significantly higher than that of the newly diagnosed patients (χ2 = 26.08, P <0.01) ), While the single drug resistance rate was significantly lower than that of the newly diagnosed patients (χ2 = 11.26, P <0.01). Conclusion The implementation of TB control strategies should be strictly followed to ensure that tuberculosis patients receive standardized and effective treatment and management to prevent the emergence and spread of drug-resistant strains.