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本文通过皮下注射不同镉锌比例的Ｃｄ－ＭＴ，来观察大鼠肾功能变化，结果显示：进入大鼠体内的镉主要在肾脏中蓄积，且随注射Ｃｄ－ＭＴ中镉的比例增高而增高；试验组肝、肾中锌的含量高于对照组，其中与Ｃｄ－ＭＴ中镉的比例有一定的关系；注射含镉比较高的大鼠其尿酶（ＮＡＧ、γ－ＧＴ）和尿蛋白（总蛋白和白蛋白）均显著高于对照组。提示：进入生物体内的镉主要以Ｃｄ－ＭＴ形式运输到肾脏；镉可影响生物体内锌的分布，且锌对镉的毒作用有一定的拮抗作用；镉性损伤以肾小管为主，一定程度可累及肾小球。
In this paper, we observed the changes of renal function in rats by subcutaneous injection of Cd-MT with different ratios of cadmium and zinc. The results showed that cadmium entering the rats mainly accumulated in the kidneys and increased with the proportion of Cd in the injected Cd-MT. The content of zinc in the liver and kidney of the experimental group was higher than that of the control group, which had a certain relationship with the proportion of cadmium in Cd-MT. The rats with high cadmium in injection had higher levels of urease (NAG, γ-GT) and urinary protein Total protein and albumin) were significantly higher than the control group. Hint: cadmium entering the organism is mainly transported to the kidney by the form of Cd-MT; cadmium can affect the distribution of zinc in the organism, and zinc has a certain antagonism on the toxic effect of cadmium; the cadmium damage is mainly in the renal tubules, Glomerular can be involved.