论文部分内容阅读
目的研究泮托拉唑、克拉霉素、阿莫西林及果胶铋四联疗法不同疗程治疗胃溃疡对患者疗效及复发率的影响。方法将206例胃溃疡患者随机分为研究组和对照组各103例。2组患者均采用泮托拉唑、克拉霉素、阿莫西林及果胶铋四联疗法进行治疗。研究组患者进行3个疗程的治疗,对照组患者进行1个疗程治疗,治疗结束后对疗效及复发率进行随访。结果 2组临床疗效差异无统计学意义(P>0.05)。2组患者1个月后HP阳性率差异不显著(P>0.05)。研究组患者1年后Hp阳性率和复发率均显著低于对照组,差异均有统计学意义(P<0.05)。结论泮托拉唑四联法治疗3个疗程的临床效果优于1个疗程,且3个疗程的复发率显著低于1个疗程。
Objective To study the effects of different courses of pantoprazole, clarithromycin, amoxicillin and pectin bismuth on the curative effect and recurrence rate of patients with gastric ulcer. Methods 206 patients with gastric ulcer were randomly divided into study group and control group, 103 cases each. Both groups were treated with pantoprazole, clarithromycin, amoxicillin and pectin bismuth quadruple therapy. Patients in the study group were treated with 3 courses of treatment, and patients in the control group were treated with 1 course of treatment. After treatment, the curative effect and recurrence rate were followed up. Results There was no significant difference in clinical efficacy between the two groups (P> 0.05). There was no significant difference in the positive rate of HP between the two groups after one month (P> 0.05). The positive rate and recurrence rate of Hp in the study group after 1 year were significantly lower than those in the control group (P <0.05). Conclusions The pantoprazole quadruple therapy is superior to one course of treatment in three courses of treatment, and the recurrence rate of three courses is significantly lower than that of one course of treatment.