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(目的)分析影响肾母细胞瘤预后的因素,探索合理、有效的治疗方案。(方法)回顾性分析158例肾母细胞瘤,计算预后好的组织结构(FH)组和预后差的组织结构(UH)组的生存率,并用卡方检验。各临床分期组的生存率用2×C表线性回归统计分析。(结果)FH组114例(72.2%)5年生存率63.3%,UH组44例(27.8%)5年生存率258%。临床分期越晚,生存率越低。(结论)病理组织分型和临床分期是影响肾母细胞瘤预后的重要因素,根据不同的组织分型和临床分期,选择合理的综合治疗方案,是提高肾母细胞瘤生存率的重要环节。
(Objective) To analyze the factors affecting the prognosis of Wilms tumor and to explore a reasonable and effective treatment plan. (Methods) A retrospective analysis of 158 cases of nephroblastoma was performed to calculate the survival rate of the well-prognosis histopathology (FH) group and the poor prognosis histopathology (UH) group and to use Chi-square test. The survival rates in each clinical stage were analyzed by linear regression with 2 × C table. (Results) The 5-year survival rate was 63.3% in 114 cases (72.2%) in FH group and 258% in 44 cases (27.8%) in UH group. The later the clinical stage, the lower the survival rate. (Conclusion) Pathological type and clinical stage are the important factors affecting the prognosis of nephroblastoma. According to different histological types and clinical stages, it is an important part to improve the survival rate of nephroblastoma by selecting a reasonable comprehensive treatment plan.