为了探讨肺心病、冠心病、肺心病并冠心病血清中apo-A_1、apo-B变化,本文测定了20例冠心病、20例肺心病、10例肺心病并冠心病apo-A和apo-B水平,并设10例健康老年人为对照组,结果表明肺心病的apo-A_1明显增高,较其他组差异显著(P<0.005),而apo-B四个组的比较,无显著差异;同时我们发现肺心病人apo-A_1变化与apo-B变化有明显正相关(r=0.66,P<0.01,?=0.038X+1.332).我们认为开展apo-A_1,apo-B的检测对肺心病;冠心病的诊断、监别诊断增添了一个新的指标,便于临床推广. In order to investigate the changes of apo-A_1 and apo-B in patients with cor pulmonale, coronary heart disease, cor pulmonale and coronary heart disease, 20 cases of coronary heart disease, 20 cases of cor pulmonale, 10 cases of cor pulmonale and apo- B level, and 10 healthy elderly people as the control group, the results showed that apo-A 1 in pulmonary heart disease was significantly higher than the other groups (P <0.005), while the apo-B four groups, no significant difference; at the same time We found a significant positive correlation between the changes of apo-A 1 and the changes of apo-B in patients with pulmonary heart disease (r = 0.66, P <0.01,? = 0.038X + 1.332) .We think that the detection of apo-A_1 and apo- ; Coronary heart disease diagnosis, differential diagnosis added a new indicator for easy clinical promotion.