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附着于血管壁上的纤溶酶原激活物,可被各种刺激因素激活,从而在防止自发血栓形成中起显著作用。有报告表明纤溶酶原激活物在怀孕期及用强地松龙、乙炔雌二醇治疗时其活性减弱,用同化激素治疗其活性增强,而孕激素如DMPA对其活性无影响。本研究以中年妇女为对象,观察年龄,使用OC时间及吸烟习惯对静脉管壁纤溶酶原活性(FAV)可能产生的影响。研究对象为68名健康的中年妇女,月经规律,年龄35至50岁,按服OC及吸烟情况分为三组。22名健康对照;第二组为19名不吸烟服用OC者(年龄中位数40岁),其中11人平均服用年限10.5年,8人平均服用2.1年;第三组为27名吸烟未服用OC者(年龄中位数40岁),其中10人吸烟量<10支/
Plasminogen activators attached to the blood vessel wall can be activated by a variety of stimuli and thus play a significant role in preventing spontaneous thrombosis. There are reports that plasminogen activator during pregnancy and with prednisolone, ethinyl estradiol treatment activity decreased, with the treatment of anabolic hormone activity increased, and progesterone such as DMPA had no effect on its activity. In this study, middle-aged women as the object, to observe the age, the use of OC time and smoking habits on the venous wall plasminogen activator (FAV) may have impact. Study of 68 healthy middle-aged women, menstrual regularity, aged 35 to 50 years old, according to OC and smoking were divided into three groups. 22 healthy controls; the second group of 19 non-smoking OC patients (median age 40 years), of whom 11 average life expectancy 10.5 years, eight people taking an average of 2.1 years; the third group of 27 smokers did not take OC (median age 40 years), of which 10 people smoked <10 /